XXII CONGRESO DE LA SOCIEDAD ESPAÑOLA DE ANATOMÍA PATOLÓGICA
Palma de Mallorca,  25 al 28 de mayo de 2005

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COMUNICACIÓN ORAL
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Sala Victoria . Día: 27 11:00. Área: 14. Infecciosas

Contacto: Clóvis Klock

Cryptococcemia. A 44- necropsies cases study of AIDS- patients in a tertiary care hospital

Klock C., Goldani L.Z., Cerski, M., Rebouças I.T.

Cryptococcus neoformans has been reported to infect most areas of the body. Cryptococcemia occurs in advanced HIV infection and usually reflects a high burden of yeasts in tissue but it can occur without an apparent secondary site of involvement.
Objective: to relate the cryptococcemia cases in patients with AIDS submitted to necropsy.
Methods: The necropsies of AIDS patients, performed at Pathology Service of HCPA between January 1988 and December 2002, were reviewed in a total of 395 cases - 44 of them had cryptococcemia. All the necropsies were performed according to the HCPA necropsy protocol. The ages of the patients varied between 9 and 68 years old. 40 of the patients were male
Description: The organs affected were: meninges and brain (28 cases), brain (8), lungs (17), spleen (22), liver (17), kidney (17), pituitary gland (14), meninges (14), pancreas (8), bone marrow (4), prostate (3), intestines (2), heart, skin and testicle (1 case each)
Conclusion: The necropsies findings show a high prevalence of spleen infection, which is not seen on the international literature

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